U.S. stock futures fell Thursday on caution after the announcement of framework agreement between Washington and Beijing and amid heightened tensions in the Middle East.
Here are some of the biggest premarket U.S. stock movers today:

Oracle (NYSE:ORCL) stock rose 9.1% after the cloud-computing group lifted its annual revenue growth target and highlighted solid demand from clients aiming to harness artificial intelligence.

Boeing (NYSE:BA) stock slumped 8.4% after an Air India aircraft–reported to be a 787-8 Dreamliner–crashed minutes after taking off from India’s western city of Ahmedabad, with 242 people on board. GE Aerospace (NYSE:GE), whose GEnx-1B engines power the 787 Dreamliner, fell 4.6%.

GameStop (NYSE:GME) stock dropped 15% after the video game retailer reported a decline in first-quarter revenue as customers increasingly opted for digital downloads over purchases at its brick-and-mortar stores.

CureVac (NASDAQ:CVAC) stock rose 29% after BioNTech (NASDAQ:BNTX) announced plans to purchase the biotech company for $1.25 billion to boost its cancer business.

Oklo (NYSE:OKLO) stock fell 6.4%, handing back some of the almost 30% gains the nuclear technology firm booked during the prior session after it was conditionally selected to provide nuclear energy to the Eielson Air Force Base in Alaska.

Palantir (NASDAQ:PLTR) stock fell 0.7%, dropping back from the previous session’s all-time high, with the big data analytics firm having gained over 80% so far in 2025.

Oxford Industries (NYSE:OXM) stock fell 10% after the high-end clothing company reported lower-than-expected earnings and revised its fiscal 2025 outlook lower.

Voyager Technologies (NYSE:VOYG) stock rose 4.5%, adding to the more than doubling since its launch, after the defense and space solutions company, secured a valuation of $3.8 billion, signalling strong interest in the sector expected to thrive under the Trump administration.